THE term "chemosurgery" was coined to designate a newly developed method for the microscopically controlled excision of certain accessible forms of cancer. The "chemo" portion of the term indicates that the tissues are chemically treated, while the "surgery" portion indicates that the tissues so treated are surgically excised. It is unfortunate, perhaps, that the term omits mention of the thorough microscopic control of excision afforded by the technic, because this control is the most important and only entirely new feature of the method.
The development of the method by experiments on animals1 and the use of the method in the treatment of various accessible forms of cancer have previously been described.2 The present article concerns the chemosurgical treatment of cancer of the nose, including the therapeutic results, in a series of two hundred and forty-three lesions treated over a nine year period.
The chemosurgical technic as applied
MOHS FE. CHEMOSURGICAL TREATMENT OF CANCER OF THE NOSEA Microscopically Controlled Method. Arch Surg. 1946;53(3):327-344. doi:10.1001/archsurg.1946.01230060334005