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Article
April 1947

PROGRESS IN ORTHOPEDIC SURGERY FOR 1945 A Review Prepared by an Editorial Board of the American Academy of Orthopaedic SurgeonsXI. INFANTILE PARALYSIS: RESEARCH

Arch Surg. 1947;54(4):459-476. doi:10.1001/archsurg.1947.01230070467009
Abstract

RESEARCHES on many fundamental questions concerning infantile paralysis continue to add little by little to existing knowledge of the disease. The various problems that beset the research worker have been presented by Gard298 in a monograph of one hundred and sixty-five pages, which does not lend itself well to detailed review.

The Virus of Poliomyelitis.  —Loring and Schwerdt299 found that the MVA purified poliomyelitis strain was stable in solution as acid as pH 1.6 but unstable below this figure and that it was stable in solution as alkaline as pH 10.3 but unstable above this figure. Olitsky300 describes the properties of a virus discovered by Theiler and Card, which he considers not to be mouse poliomyelitis of either natural or experimental type. He states that the difference between it and other strains of mouse poliomyelitis virus is such as to make it entirely unsuitable

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