October 1949

PROGRESS IN ORTHOPEDIC SURGERY FOR 1946 A Review Prepared by an Editorial Board of the American Academy of Orthopaedic SurgeonsXVII. INFANTILE PARALYSIS: RESEARCH

Arch Surg. 1949;59(4):957-970. doi:10.1001/archsurg.1949.01240040966017

VIRUS STUDIES  SCHLESINGER and others738 report that three strains of poliomyelitis virus were isolated in cases in the British Army in the Middle East. Two strains may have been related to the Lansing type, one being easily transmitted to rodents and the other being serologically of the Lansing type but not transferable; the remaining strain was not related at all and not transferable.Olitsky and Findlay739 make a similar report of a strain isolated in the case of a soldier with poliomyelitis in the Middle East. It was demonstrated that the strain could be substituted for the Lansing strain in neutralization tests in mice for epidemiologic purposes.Kabat and others740 state that the lactic acid content of the brain is significantly decreased in mice infected with the virus of poliomyelitis. This factor appears to be additional evidence for the theory that the virus may interfere in a

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