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Article
December 1949

PROGRESS IN ORTHOPEDIC SURGERY FOR 1946 A Review Prepared by an Editorial Board of the American Academy of Orthopaedic SurgeonsXXI. RESEARCH

Author Affiliations

WILMINGTON, DEL.

Arch Surg. 1949;59(6):1346-1362. doi:10.1001/archsurg.1949.01240041360014
Abstract

THE LITERATURE on orthopedic research and related subjects for 1946 shows a preponderance of articles on changes in the bone associated with hormones. However, there are no outstanding articles among this group. Seventy-one articles were abstracted for this review, and thirty-one have been selected as references. They are divided into the following subjects: (1) changes in the bone, associated with hormones and other substances; (2) biochemical studies; (3) anatomic and physiologic studies; (4) studies of muscle; (5) studies of cartilage, fascia and joint; (6) fluorine studies, and (7) miscellaneous research.

CHANGES IN THE BONE, ASSOCIATED WITH HORMONES AND OTHER SUBSTANCES 

M. and R. Silberberg1043 state:  In immature male mice, testosterone propionate accelerated the ageing of the epiphyseal cartilage by inhibiting proliferation and by increasing regressive changes. These effects were less marked in males than in immature females. Removal of the testicles caused a delay in the development of the

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