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February 1950


Author Affiliations

From the Department of Orthopaedic Surgery, University of Illinois.

Arch Surg. 1950;60(2):294-304. doi:10.1001/archsurg.1950.01250010312009

IN 1935 JAFFE described a benign tumor of bone which had escaped recognition for a number of years and was frequently misdiagnosed as "sclerosing nonsuppurative osteomyelitis of Garré," "osteomyelitis with annular sequestrum" or "bone abscess," especially when the tumor was present in cortical bone. He defined the neoplasm as follows:

The lesion is a benign osteogenic tumor of slow growth. The initial phase of its evolution in a given site seems to be the proliferation of the local bone-forming mesenchyme and particularly of its osteoblasts.1

Although the neoplasm proper (osteoid-osteoma) measures only about 1 cm. in diameter, the surrounding bone may show considerable thickening (sclerosis).

ETIOLOGY  The etiology of this growth, like that of all other neoplasms, is unknown. Dr. Dallas B. Phemister described the lesion as a localized osteomyelitis of a chronic nature; however, at the present time he has discarded this view.2 Although a history of

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