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Article
March 1950

GENERALIZED GIANT HYPERTROPHIC GASTRITIS SIMULATING NEOPLASMDifferential Diagnosis and Report of a Case

Author Affiliations

CHICAGO
From the Department of Surgery of the University of Chicago.

Arch Surg. 1950;60(3):543-558. doi:10.1001/archsurg.1950.01250010562011
Abstract

IN A COLLECTIVE review of medical publications up to July 1942, Pack and McNeer reported only 2 total gastrectomies for benign lesions among 303 authenticated total gastrectomies. Wier stated that 9 total gastric resections have been performed for benign gastric lesions at the Mayo Clinic between 1935 and 1944. Jones (1945) reported 2 resections for benign ulcers close to the cardia among 8 total gastrectomies in which no postoperative deaths occurred. The case being reported and 1 subsequent case observed in Billings Hospital are the only 2 of generalized hypertrophic gastritis in which total gastrectomies are known to have been performed.

Hypertrophic gastritis is characterized by hypertrophy and hyperplasia of the gastric mucosa. Focal areas of mucosa or, as in the case reported, nearly the entire mucosa may be involved. Only 45 cases of hypertrophic gastritis have been found in which the diagnosis has been supported by pathologic studies (see

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