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Article
October 1950

SPONTANEOUS CLOSURE OF THE PORTACAVAL ANASTOMOSIS IN THE EXPERIMENTAL ANIMAL

Author Affiliations

CHICAGO
From the Department of Surgery, Northwestern University Medical School. Aided by the Grunow Surgical Fund.

AMA Arch Surg. 1950;61(4):661-666. doi:10.1001/archsurg.1950.01250020667006
Abstract

THERE has been an interest in venous fistulas since 1877, when Eck1 first suggested a technic for producing a portacaval anastomosis. Since that time many studies of the physiologic changes produced in animals by an Eck fistula have been reported.

Blalock,2 Blakemore3 and Whipple4 have reported that a side to side portacaval fistula without obstruction of the portal vein will close, but to date no specific report of experimental work has been found in the literature. A similar fistula will remain patent in the typical animal with an Eck fistula, in which the portal vein is occluded.5

A few clinical cases have been reported in which there were recurrent gastrointestinal hemorrhages after the establishment of a portacaval fistula. It seems possible that this may be due to closure of the fistula in some instances. Many factors contribute to the maintenance of the patency of a

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