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Article
September 1951

LIGATION OF HEPATIC AND SPLENIC ARTERIES IN TREATMENT OF PORTAL HYPERTENSIONLigation in Atrophic Cirrhosis of the Liver

Author Affiliations

INDIANAPOLIS
From the departments of surgery of the Indianapolis General Hospital and the Indiana University Medical Center.

AMA Arch Surg. 1951;63(3):379-389. doi:10.1001/archsurg.1951.01250040385013
Abstract

IN A PREVIOUS communication1 we reviewed the clinical causes and the present-day methods of treatment of portal hypertension. We also discussed the physiology of the hepatic circulation, and one of us (J. K. B.) presented the results of experimental work on portal hypertension since March, 1947. This work may be summarized briefly as follows:

1. Survival After Ligation of Hepatic Artery

A. Without preparation with penicillin and streptomycin

1. Ligation close to liver caused death due to liver necrosis and gangrene of gall bladder with bile peritonitis

2. Ligation at source caused death due to liver necrosis and gangrene of gall bladder, with bile peritonitis in many instances

B. Preparation with penicillin and streptomycin

1. Ligation close to liver caused death due to liver necrosis

2. Ligation at source resulted in survival if dogs were cared for properly

II. Collateral Circulation After Ligation of Hepatic Artery at Source

A.

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