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Article
October 1951

GROWTH OF VASCULAR GRAFTS IN GROWING EXPERIMENTAL ANIMALSA Preliminary Report

Author Affiliations

CHICAGO
From the Department of Surgery, University of Illinois College of Medicine.

AMA Arch Surg. 1951;63(4):576-582. doi:10.1001/archsurg.1951.01250040588020
Abstract

IN RECENT years there has been an increasing use of venous and arterial grafts in the operative correction of various congenital vascular anomalies in infants and children.1 There is, however, little or no evidence to indicate whether or not these vascular grafts grow as the patient increases in size. In an attempt to answer this question, various types of vascular grafts have been utilized to bridge experimentally produced aortic defects in growing animals.

METHOD OF STUDY  Young weanling pigs were selected as experimental animals because of their known capacity for marked increase in size over a short time. With the animals under ether anesthesia the abdominal aorta was exposed retroperitoneally through a lumbar incision. An aortic segment approximately 15 mm. in length was removed between clamps and the defect bridged by an autogenous arterial graft, an autogenous venous graft or a preserved homologous arterial graft. The Carrel technique of

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