PHASES of the problem of restoring and maintaining nutrition in the sick patient have been the subject of investigation at the Medical Research Foundation of Dade County during the past four years. Intermittent intravenous and enteral feedings have been considered, and as a result of our studies it is apparent that continuous-drip feeding solutions containing an excess of amino acids and calories administered by tube into the gastrointestinal tract provide the best means for restoring and maintaining nutrition. Herein are reported details of the successful solution of certain problems confronting patients who cannot or will not eat.
Limitations imposed on attempts to maintain nutrition by intermittent intravenous administration of nutrient solutions redirected our efforts to the gastrointestinal tract. The important basic observation of Elman1 that incomplete mixtures of amino acids cannot be utilized in the synthesis of body protein even when the missing essential amino acid is provided
ELLIOTT J, SMITH DW, GRIFFITTS JJ, LEWIS GT, FERRO PV. NEW REGIMEN IN FEEDING THE CRITICALLY ILLPreliminary Report. AMA Arch Surg. 1952;64(3):278-285. doi:10.1001/archsurg.1952.01260010292002