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Article
May 1952

INTESTINAL-BILIARY REFLUX AFTER ANASTOMOSIS OF COMMON DUCT TO DUODENUM OR JEJUNUMAn Experimental Study

Author Affiliations

ALBUQUERQUE, N. M.; ROCHESTER, MINN.
From the Lovelace Clinic, Albuquerque, N. M. (Dr. Musgrove), and the Division of Experimental Medicine, Mayo Foundation, University of Minnesota (Dr. Grindlay and Dr. Karlson).

AMA Arch Surg. 1952;64(5):579-589. doi:10.1001/archsurg.1952.01260010597007
Abstract

THE IMPORTANCE of reflux of intestinal content into the biliary tract as a cause of ascending cholangitis and biliary cirrhosis following anastomosis between the biliary and the gastrointestinal tracts has been a subject of discussion for some time. With the hope of adding to our knowledge of this subject, three different surgical procedures have been performed on three groups of dogs, in which cholecystectomy and stricture of the common duct had previously been accomplished. In the first group, side-to-side choledochoduodenostomy was performed. In the second group, side-to-side choledochojejunostomy was carried out between the duct and an intact loop of jejunum. In the third group, side-to-side choledochojejunostomy was established in a so-called defunctionalized or antiperistaltic limb of jejunum after the method of Roux.

METHODS  All dogs had preliminary cholecystectomy and partial occlusion of the common duct. The latter procedure was carried out by crushing the distal portion of the common duct

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