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Article
July 1953

POSTOPERATIVE LOSS OF SUGAR IN URINE FOLLOWING INTRAVENOUS INFUSION OF FRUCTOSE (LEVULOSE)

Author Affiliations

ST. LOUIS
From the Department of Surgery, Washington University School of Medicine, Barnes Hospital, St. Louis, and Veterans Administration Hospital, Jefferson Barracks, Mo.

AMA Arch Surg. 1953;67(1):57-60. doi:10.1001/archsurg.1953.01260040060009
Abstract

IN A PREVIOUS report1 the urinary losses of sugar following the intravenous infusion of fructose (levulose) and of D-glucose (dextrose) were compared in an unselected group of patients. In the present study a similar comparison was made in patients during the immediate postoperative period. No other observations have been reported thus far on the behavior of fructose given by intravenous infusion after operation.

METHODS  Observations were made in two groups of patients. In the first group there were 10 patients all well nourished and undergoing various major surgical procedures under general anesthesia. During each of the first four postoperative days, 2 liters of 10% sugar was infused, using on alternate days 10% fructose2 and 10% dextrose. On the first day, six patients were given dextrose and four fructose. An attempt was made to give each infusion at the same rate, but in each case the duration was measured

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