The first use of vagotomy in the treatment of gastrojejunal ulcer at the Mayo Clinic was in 1945. In the years 1945 to 1952 inclusive, 617 operations were performed on 586 patients for gastrojejunal ulcer. One hundred and forty-three of these operations consisted of vagotomy alone or of vagotomy combined with additional procedures, while 474 were operations in which vagotomy was not done. The latter operations consisted primarily of gastric resection. The 143 patients who underwent vagotomy will be called the "vagotomy group."
A group of 158 patients treated for gastrojejunal ulcer by gastric resection or gastric re-resection during the same interval was studied also and this will be referred to as the "resection group." *
The 301 cases included in this study were divided into two groups: 115 cases in which gastrojejunal ulcer occurred after gastric resection, and 186 cases in which gastrojejunal ulcer occurred after gastroenterostomy. By analyzing these
WALTERS W, CHANCE DP, BERKSON J. The Surgical Treatment of Gastrojejunal Ulcera tion. AMA Arch Surg. 1955;70(6):826-832. doi:10.1001/archsurg.1955.01270120034005