April 1956

An Apparatus and Technique for Freeze-Drying Arterial Homotransplants

Author Affiliations

Iowa City
From the Department of Surgery, State University of Iowa College of Medicine. Assistant Professor (Dr. Taber), Assistant Resident (Dr. Goslin), Professor (Dr. Ehrenhaft), and Professor and Head of Department (Dr. Tidrick).

AMA Arch Surg. 1956;72(4):644-648. doi:10.1001/archsurg.1956.01270220092012

The concept of arterial storage and substitution, as developed experimentally by Carrel * and Guthrie12 at the turn of the century and later successfully applied clinically by Blakemore,3 Hufnagle,13 and Gross,11 is now established as a practical and dependable procedure. A growing clinical experience with arterial substitution, as reported by Dubost,9 Swan,25 Julian,17 and De Bakey and Cooley,8 has further emphasized the usefulness of arterial homotransplantation in the surgical management of obstructive and aneurysmal diseases of the major vessels. Until such time as the synthetic fiber fabric substitutes demonstrate an equally satisfactory solution to both large- and small-vessel substitution problems, it would appear worth while for the surgeon treating these conditions to have access to stored arterial homotransplants. Among the several methods of arterial transplant storage currently in use, the freeze-drying technique has been found most desirable by many investigators.† The most conspicuous

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