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February 1957

Partial Hepatectomy Employing Differential HypothermiaAn Experimental Study

Author Affiliations

Naval Medical Research Institute, National Naval Medical Center, Bethesda, Md.

AMA Arch Surg. 1957;74(2):189-200. doi:10.1001/archsurg.1957.01280080039004

Introduction  Surgeons attempting hepatic resection are confronted with the problem of hemostasis in an extremely vascular and friable organ. Oozing from the cut surface of the liver results in considerable blood loss and obscures the operative field, making control of hemorrhage difficult.There are numerous indications for an improved technique for partial hepatic resection. One such indication is primary carcinoma of the liver. Halpert and Erickson report an apparent or real increase in the incidence of this neoplasm.1 In their series of 28 cases from an autopsy population of 1400, the tumor is believed to have been the direct cause of death in 16. Thirteen patients died without evidence of distant spread of the disease.Embolic metastatic lesions frequently involve the liver and, while usually multiple, may be solitary. Neoplasms of the gallbladder, stomach, and colon are occasionally found to extend directly into the liver, and good results have

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