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February 1957

Myocardial RevascularizationExperimental and Clinical Critique

Author Affiliations

From the Department of Surgery, Chicago Medical School; the Cardiovascular Department, Medical Research Institute, Michael Reese Hospital and the Department of Surgery, Michael Reese Hospital.

AMA Arch Surg. 1957;74(2):225-231. doi:10.1001/archsurg.1957.01280080075012

Introduction  The greatest killer of the adult American male is coronary artery heart disease, a degenerative process associated with atherosclerosis, a disease of aberrant metabolism of fat. Surely, the solution of the problem of atherosclerosis and with it of coronary artery heart disease, as of any degenerative process, must be medical in nature. When enough facts are assembled clinically and experimentally on the subject of the metabolism of cholesterol and other fats and the reasons why they are deposited on the intima of some vessels and not of others, in some people and not in others, in one part of the world more and another part of the world less—and when the presence of these aberrations can be detected clinically and then treated medically—then the treatment of coronary artery heart disease will be exclusively medical in nature. Until that happy day, however, the pursuit of a means to lengthen the

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