The anorectum is the third most frequent site of origin of malignant melanoma, following only the skin and eyes. Malignant melanotic tumors originating at this junction spread by direct extension, by lymphatic pathways, and via the blood stream. Accordingly, they have been treated by radical surgical intervention, which has usually included an abdominoperineal resection, followed in some instances by block dissection of ileoinguinal lymph nodes. Despite such drastic therapeutic measures, results have been uniformly poor, and survival for three years or longer has been unusual.
The case reported here is that of a patient who remains alive and well, without evidence of recurrence or metastasis, 43 months after therapy consisting only of a wide local excision.
Report of Case
The patient was a 65-year-old married white woman whose chief complaint on admission was of occasional episodes of rectal bleeding for six months. During the same period she had had intermittent
PROBSTEIN JG. Malignant Melanoma of the AnorectumReport of a Case Without Recurrence Forty-Three Months Following Only Local Excision. AMA Arch Surg. 1957;75(2):253-255. doi:10.1001/archsurg.1957.01280140091015