September 1957

Plastic Grafts for Aortic Substitution in Man

Author Affiliations

From the Department of Surgery, Indiana University Medical Center.

AMA Arch Surg. 1957;75(3):413-422. doi:10.1001/archsurg.1957.01280150103011

A steadily increasing need for blood vessel substitutes has arisen as a result of recent advances in the treatment of aneurysms, coarctation of the aorta, and obstructive lesions of the aorta and major arteries. Autogenous veins may be used for peripheral arterial grafts but are not suitable for aortic replacement. Preserved homologous arteries have, in general, served well. They are, however, difficult to procure in adequate numbers. They have the additional theortical disadvantages of not surviving as living structures and of being subject to late degenerative changes. In at least a few instances, they have been followed by aneurysmal dilatation or disruption. It has, therefore, seemed logical to inquire into the possibility of using inert plastic grafts. Voorhees, Jaretzki, and Blakemore1 were the first to demonstrate that tubes of Vinyon N cloth could be employed successfully for grafts to the canine aorta. Shortly afterward my associates and I began

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