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June 1958

Distribution of Radioactive Tryptophan in a Patient with Metastatic Carcinoid

Author Affiliations

Departments of Surgery and Pediatrics, University Hospitals of Cleveland and Western Reserve University School of Medicine.

AMA Arch Surg. 1958;76(6):912-913. doi:10.1001/archsurg.1958.01280240070011

In a previous report1 attention was called to the direct uptake of radioactive tryptophan by metastatic carcinoid tumor in vivo, demonstrated in a patient known to harbor this tumor prior to laparotomy.

An opportunity to obtain additional data in a similar case was recently afforded us, and it seems worthy of recording these in the light of the rarity of these tumors and their pharmacological significance.

This patient was admitted to the hospital with a diagnosis of small-intestine obstruction. Laparotomy was performed and revealed the presence of a tumor in the terminal ileum which was narrowing the lumen of the small bowel. The tumor and adjacent small bowel were resected and intestinal continuity reestablished. Palpation of the surface of the liver at the time of surgery disclosed a small solitary nodule, thought to represent metastatic tumor. The patient's postoperative course was uneventful, and the pathologist reported the primary tumor

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