[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.204.198.71. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
August 1958

Neurofibrosarcomas of Cranial Nerve Origin

Author Affiliations

Chicago
From the Department of Surgery, University of Illinois College of Medicine.

AMA Arch Surg. 1958;77(2):271-281. doi:10.1001/archsurg.1958.01290020121023
Abstract

Neurofibrosarcomas of the head and neck are uncommon. The difficulties encountered in their proper care are of such complexity that an appraisal of their clinical course and surgical management is indicated.

Since they were first described, there has been little unanimity of opinion regarding the cell origin of these tumors, and accordingly they have been called by a variety of names. Some authors1-3 have stressed their Schwannian origin and thus call them malignant schwannomas. They have also been designated by the synonyms of neurogenic sarcoma,4,5 neurosarcoma,6 and neurofibrosarcoma.7 We prefer the last term because it is well established and easily understood and because it describes the histological appearance without entering into the controversy of its cellular derivation.

The clinical appearance of neurofibrosarcomas is not diagnostic. In the area under discussion they are usually of small or medium size, resilient, smooth, and occasionally painful. Ulceration occurs only

First Page Preview View Large
First page PDF preview
First page PDF preview
×