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November 1958

Experimental Artery Graft AngulationA Comparison Study with Dacron Collapsible Tubing, Tapp-Edwards Crimped Nylon Prosthesis, and Freeze-Dried Preserved Artery Homograft

Author Affiliations

Madison, Wis.
From the Department of Surgery and the Cardiovascular Laboratory (Dr. Charles W. Crumpton, Director), University of Wisconsin Medical School.

AMA Arch Surg. 1958;77(5):804-806. doi:10.1001/archsurg.1958.01290040152019

The development of collapsible and non-collapsible synthetic cloth prostheses, suitable for replacing segments of the arterial tree, has led us to investigate their use in conditions that favor angulation and kinking of the graft. We have selected for comparison study (a) a collapsible prosthesis, (b) a flexible prosthesis, and (c) a preserved artery homograft. As this problem of graft angulation has been afforded little emphasis with respect to the selectivity of some of the newer cloth prostheses, this study is presented to emphasize the importance of graft flexibility in order to delineate further the criteria in selecting the proper artery substitute.

Method of Study  Adult mongrel dogs were used. Intravenous pentobarbital (Nembutal) anesthesia and sterile technique were employed for each operation. Through separate incisions, the common iliac artery and femoral artery were isolated. The former was divided approximately 2 cm. below the aortic bifurcation; the latter, 3 cm. distal to

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