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Article
September 1959

Controlled Radio-Frequency Generator for Production of Localized Heat in Intact AnimalMechanism and Construction

Author Affiliations

Chicago
From the Surgical Research Laboratories, Presbyterian-St. Luke's Hospital.; All isotope determinations were performed by Dr. John Clark, Attending Radiologist, Presbyterian Hospital.; Rauland-Borg Corporation (Mr. Medal); Clinical Assistant Professor of Surgery, University of Illinois College of Medicine (Dr. Shorey); Clinical Professor of Surgery, University of Illinois College of Medicine (Dr. Gilchrist); Resident in Surgery, Presbyterian Hospital (Dr. Barker); Clinical Assistant Professor of Surgery, University of Illinois College of Medicine (Dr. Hanselman).

AMA Arch Surg. 1959;79(3):427-431. doi:10.1001/archsurg.1959.04320090075011
Abstract

In our previous paper1 we have shown that it is possible to produce differential heating in vitro in an electromagnetic field. his heating is dependent on the radio frequency, on the magnetic field strength, and on the coercive force of the magnetic particles of Fe2O3, which are 0.02μ-0.1μ in size and which serve as the target material. In this paper we will demonstrate that we can produce differential heating in the intact animal even to the point of localized tissue necrosis. Examples of the temperature changes in the normal tissues during treatment will be shown. We will describe the apparatus for recording this temperature and also the characteristics of the radio-frequency field used.

The contribution of the electronic scientist in this medical research program has been threefold: First, it was necessary to develop a radio-frequency generator and work coil; second, several types of magnetic particles had

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