October 1959

Removal of Sodium-Copper Chlorophyllin from Solutions by Washed Human Red Blood Cells

Author Affiliations

Fort Howard, Md.
Surgical Service (Dr. Miller) and General Medical Research Service (Mr. Collier and Miss Jackson), Veterans Administration Hospital.

AMA Arch Surg. 1959;79(4):617-620. doi:10.1001/archsurg.1959.04320100083015

The reasons for obtaining excellent clinical results from the use of the watersoluble derivatives of chlorophyll in the treatment of infected wounds have not been fully determined. A small amount of evidence from the laboratory and a large amount of clinical data attest, however, to the efficacy of the drug in this condition.

Dunham,11 in studying the influence of chlorophyll on fibroblasts in tissue culture, reported that in all instances the fibroblasts grew more luxuriantly in the cultures containing chlorophyll than in the controls. He concluded that preparations containing proper concentrations of chlorophyll would have similar effects on fibroblasts in wounds which were in the process of healing.

Buergi7 found that chlorophyll produced faster healing in experimentally produced wounds in guinea pigs and rabbits than any other preparation. The depths of the wounds dried; rich granulation tissue grew promptly; growth of epithelium was found; the wounds became smaller,

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