February 1960

Stored Skin Homografts in Extensively Burned Patients

AMA Arch Surg. 1960;80(2):208-213. doi:10.1001/archsurg.1960.01290190028006

This report of 50 extensively burned patients treated with stored split-thickness skin homografts is a result of a clinical research effort which began in 1951. All of the skin homografts in this study were procured, processed, and stored by the Tissue Bank * of the Naval Medical School. This investigation presents data which permit a rough comparison between the mortality rate of burned patients who were treated with fresh1,2 and those treated with stored skin homografts.

At the outset it was important to determine whether or not stored skin, viable or nonviable, could approximate the clinical "take" and remain as a biological dressing in a manner which was the equivalent of the fresh homograft. In the instance of the stored viable skin, this did not appear to be questionable, and indeed it was not. In the instance of the known nonviable freeze-dried skin, this question was paramount. In the very

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