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October 1960

Radiation Ileitis

Author Affiliations

Stamford, Conn.

Arch Surg. 1960;81(4):553-557. doi:10.1001/archsurg.1960.01300040037007

The effects of excess radiation on the colon, rectum, and bladder and their surgical complications are well known. Radiation damage to the small intestine is less frequent, and the operative complications have rarely found their way into the surgical literature. With modern intensive radio-therapeutic measures the incidence of damage to the small intestine may become more frequent.

R. M. Mulligan1 summarized all cases of injury to the gastrointestinal tract by radiation starting with the first reported cases by Walsh in 1897.2 He first demonstrated the specific pathological changes in the ileum following radiation and reported an additional case with autopsy findings. Warren and Whipple3 reported on the sensitivity of the small intestine to radiation and the histological changes which follow. T. E. Jones4 reported on benign strictures of the intestine following radiation. In 38 cases showing the effects of excess radiation on the gastrointestinal tract Warren

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