In a previous publication1 we reported that general factors such as age, sex, race, occupation, birthplace, and weight loss, affect the incidence, type, and outcome of acute peptic ulcer perforations. Other factors, such as season at time of occurrence, alcohol, marital status, dietary habits, sleeping habits, and home environment were without apparent influence.
In this report we wish to present the data of prognostic value contained in the symptoms and signs of the same group of 1,904 patients with acute gastroduodenal perforations. The records of these patients were surveyed from the Cook County Hospital's confirmed peptic ulcer population of 8,451 patients cared for during the 20-year period from 1936 through 1955. The detailed method of collecting such a large volume of clinical data was facilitated by the use of a syllabus containing a coding system and was processed by 2 registered nurses who had had experience as medical historians.
KOZOLL DD, MEYER KA. Symptoms and Signs in the Prognosis of Gastroduodenal UlcersAn Analysis of 1,904 Cases of Acute Perforated Gastroduodenal Ulcer. Arch Surg. 1961;82(4):528-544. doi:10.1001/archsurg.1961.01300100042004