With the introduction of mammography1-4 it has become possible not only to identify nonpalpable lesions within the breast but also, in most cases, to predict the nature of the lesion itself. Mammography may also be of assistance in determining the nature of the "dominant lump" when multiple breast nodules are palpable. Mammography, however, is not a substitute for surgical biopsy and microscopic examination of the tissue removed.
Benign lesions are usually sharply circumscribed with little or no reaction detectable in the adjacent tissue when roentgenographically examined (Fig. 4). Malignant ones frequently are irregularly marginated with strands of radiopaque tissue extending peripherally, and they frequently contain small calcific opacities as well as increased vascular markings within adjacent breast tissue (Fig. 2).
During the past 5 years, 10,250 roentgenographic examinations have been carried out on a group of 1,300 asymptomatic women. When possible, each patient was examined twice a year. An
BERGER SM, GERSHON-COHEN J, BEHREND A. The Earlier Diagnosis of Breast CarcinomaX-Ray Diagnosis of Nonpalpable Malignant Lesions of the Breast. Arch Surg. 1963;86(2):308-312. doi:10.1001/archsurg.1963.01310080132030