Controversy still exists about the proper form of therapy for epidermoid carcinoma of the anus. Radiotherapy as the primary treatment,12,14 local excision for small carcinomas of the anal margin,1,4,6 and "prophylactic" groin dissections after abdominalperineal resection3,5-9,11 all have advocates. This study reports the experience with 79 persons treated for epidermoid carcinomas of the anus at the Ellis Fischel State Cancer Hospital and the Barnes Hospital from 1940 through 1957. A comparison of the various therapeutic methods used to treat these patients shows that abdominal-perineal resection was the most effective therapy employed.
Data on the pathological anatomy, size of the primary tumors, host age and sex distributions, metastases, therapies employed, and host survival after treatment for the 79 epidermoid anal carcinomas studied are shown in Tables 1 to 5. All patients were followed five or more years after treatment or to death. All histological sections were re-examined
DILLARD BM, SPRATT JS, ACKERMAN LV, BUTCHER HR. Epidermoid Cancer of Anal Margin and CanalReview of 79 Cases. Arch Surg. 1963;86(5):772-777. doi:10.1001/archsurg.1963.01310110082012