Since the malignant potential of solitary pulmonary nodules was first emphasized,1-3 a number of papers have inferred the same dismal prognosis for bronchogenic carcinoma presenting as a solitary nodule as for bronchogenic carcinoma in general.4-7 Thereby the value of roentgen survey in the early detection of pulmonary carcinoma has been questioned as well.
Recently survival rates much better than those usually attributed to bronchogenic carcinoma8-15 have been recorded16-26 for the malignant solitary nodule.
During the period of January, 1952, to January, 1957, a total of 46 patients with bronchogenic carcinoma manifested as a solitary pulmonary nodule were treated by us. The results of the experience with this small group of patients emphasizes several facets in the management of this form of carcinoma.
In this group of patients there was the usual sex ratio and age distribution. There were 38 males and 8 females ranging in age
O'CONNOR TM, LEPLEY D, WEISEL W, WATSON RR. The Malignant Solitary Pulmonary Nodule Follow-Up Study. Arch Surg. 1963;86(6):985-988. doi:10.1001/archsurg.1963.01310120103016