July 1963

Effect of Chemical Agents on Bronchogenic Cancer

Author Affiliations

Associate Clinical Professor of Surgery University of Cincinnati, College of Medicine (Dr. Maurer).; Director of Chemotherapy, Christ Hospital and Bethesda Hospital (Dr. Freckman).

Arch Surg. 1963;87(1):147-153. doi:10.1001/archsurg.1963.01310130149019

Introduction  In an informative article written during 1957, Budinger2 concluded with the following statement:That such a large series of terminal patients is easily accumulated testifies to the subtlety of bronchogenic carcinoma and perhaps to the failure of patient education in this group. At present, the great majority of patients with lung cancer at Boston City Hospital are seen too late to permit an attempt at definitive therapy.Hayward5 made the following observation:... if a hint that surgical successes are few creeps in [the literature], it is fashion to counter it by a call for earlier diagnosis, thus creating the impression that this will correct the position. I... do not believe that earlier diagnosis [of lung cancer] will increase surgical "cures" to a really significant percentage.... surgery of carcinoma of the lung is depressing.... The idea that more extensive operations or more powerful X-ray machines will go an

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