During extracorporeal perfusion multiple factors effect the coronary arterial pressure. Two of the most significant factors are controllable because they are functions of the bypass, viz, (1) the rate of flow and (2) the temperature of the perfusate. A third important factor, controllable by the surgeon during the operative procedure, is left heart decompression. Finally a fourth factor, only in part controllable, is ventricular fibrillation. The following report is an assay of the effect of these four factors on coronary arterial pressure.
Coronary arterial blood flow is approximately 5% of total cardiac output.3,12 In the dog, the right coronary, carrying 20% of the total coronary flow, supplies the right auricle, interauricular septum, and a small portion of the right ventricle.3,12 In this experiment the left coronary artery, carrying 80% of the total coronary flow to the remaining portions of the heart, was chosen for cannulation and perfusion. Left
MEYER EG, FALOR WH. Coronary Artery Pressure in the Perfused Heart. Arch Surg. 1963;87(5):805-809. doi:10.1001/archsurg.1963.01310170091016