October 1964

Changes in Red Cell Mass After Pelvic Fracture

Author Affiliations

Resident in Orthopedic Surgery (Dr. Zeidman), Professor of Orthopedic Surgery, Chairman of Division (Dr. Wray), Upstate Medical Center.; Division of Orthopedic Surgery, Department of Surgery, State University of New York, Upstate Medical Center.

Arch Surg. 1964;89(4):596-601. doi:10.1001/archsurg.1964.01320040012003

Introduction  Those concerned with fracture management have frequently implied that closed and uncomplicated fractures may be associated with large losses of blood. A review of the literature, however, has failed to uncover experimental evidence to substantiate this opinion. Accordingly, a series of studies has been carried out in an effort to determine the effects of varying types of fracture upon the circulating red cell mass of the splenectomized dog.The initial study of the experimental program was performed with a series of dogs that were subjected to closed fractures of one or more long bones. Contrary to expectations, such injuries were followed by minimal blood loss at the fracture site and by an increase in the circulating red cell mass as measured with radiochromate.1The present investigation is concerned with the effect of pelvic fracture upon the circulating red cell mass. Fractures of the pelvis have been produced in

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