Freezing the mucosa of the stomach has been reported to achieve a physiologic gastrectomy with a profound depression of gastric secretion.1 Initial studies reported this to be a safe and effective method of treatment. However, subsequent investigations have not seemed to substantiate these early good reports, and various editorials and clinical studies have interjected serious reservations about this new mode of therapy.2-5 This study was initiated in March of 1962. A total of 21 patients had a peptic ulcer diathesis treated by gastric freezing. Prior to undertaking clinical work, the investigators spent sufficient time in the dog laboratory to thoroughly familiarize themselves with all the technical aspects of gastric freezing.
Selection of Patients.
—The patients ranged in age from 24 to 74 years. There were 19 males and two females. Some patients had the possibility of gastric freezing suggested to them as a means of controlling their
KAUVAR AJ, KARSH HB, HERMANN G. Gastric FreezingA Clinical Evaluation. Arch Surg. 1964;89(6):985-988. doi:10.1001/archsurg.1964.01320060053010