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Article
December 1964

Prevention of Adhesions With PolyvinylpyrrolidonePreliminary Report

Author Affiliations

HARLAN, KY

Arch Surg. 1964;89(6):1011-1015. doi:10.1001/archsurg.1964.01320060079015
Abstract

Introduction  The problem of re-formation of abdominal adhesions after their lysis is still a challenging one in surgery. Beyond special consideration of the surgical techniques, there has been no definitive, generally acceptable method to combat adhesions reported in the literature. The Noble plication is not a preventive method. It has tended to minimize the complications resulting from abdominal adhesions by the fashioning of planned, nonobstructing adhesions, but it is a tedious procedure which produces irreversible changes within the peritoneal cavity. From experimental work in this field, the idea of preventing formation of abdominal adhesions by the introduction of artificial ascites attracted our interest. It seemed logical that keeping the raw surfaces of the previously adherent organs from direct contact for a period of seven-ten days might prevent the re-formation of the adhesions because the raw areas would then have a chance for reperitonealization. Review of the literature1-3 reveals that

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