Carcinoid tumors are derived from Kultschitsky cells or their precursors and have the potential to produce serotonin 5-hydroxytryptamine or 5-hydroxytryptophan. The predominance of carcinoids in the intestinal tract is well known, especially in the region of the ileocecal valve where Kultschitsky cells are numerous. In order of frequency, carcinoids are found in the appendix, small intestine, large intestine, and stomach. Carcinoids of the biliary tract are rare.
In 43 cases of carcinoid tumors seen at the Veterans Administration Hospital in the past ten years, there was one instance of this neoplasm in the gallbladder. This case, as well as a review of the world's literature, comprise the present report.
Report of a Case
A 71-year-old male was admitted to the Veterans Administration Hospital with complaints of abdominal swelling, weakness, weight loss of 28 lb (12.7 kg), and generalized pruritis without rash or jaundice for three months.
SHIFFMAN MA, JULER G. Carcinoid of the Biliary Tract. Arch Surg. 1964;89(6):1113-1115. doi:10.1001/archsurg.1964.01320060181033