February 1965

Staphylococcal Sepsis and Patient's Nasal-Carrier State

Author Affiliations

From the departments of surgery and preventive medicine, State University of New York Upstate Medical Center, and the Surgical Service, Veterans Administration Hospital. Chief of Surgery, Veterans Administration Hospital, Associate Professor of Surgery, State University of New York, Upstate Medical Center (Dr. Rogers); Bacteriologist, Veterans Administration Hospital, Clinical Teaching and Research Assistant in Microbiology, State University of New York, Upstate Medical Center (Mr. Duffy); Attending Physician, Veterans Administration Hospital, Associate Professor, Preventive Medicine, State University of New York, Upstate Medical Center (Dr. Mou).

Arch Surg. 1965;90(2):294-297. doi:10.1001/archsurg.1965.01320080118025

THE PROBLEM of infection with staphylococci during hospitalization is a threat to every patient admitted to a surgical service. Although there seems to have been a considerable decline in the rate of such infections since the late 1950's, every surgical ward continues to have instances of staphylococcal sepsis. As shown by Burke1 and Culbertson et al2 the source of the infecting organism and the reasons for clinical infection are undoubtedly multiple. The individual's own nares have been frequently incriminated as the source of the contaminating organism. Weinstein,3,4 Colbeck et al,5 Elek and Fleming,6 and Williams et al7 feel that this is an important source of such hospital acquired infection. Also it has been suggested by Weinstein,3,4 Williams et al,7 and Gillespie et al8 that elimination of staphylococci from the nasal passages of patients by antibiotic ointments or sprays might decrease the

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