A REPORT on the structural changes in the canine stomach following gastric freezing has indicated that little human material is available for study.1 During a period of 14 months 90 patients having peptic ulceration of the duodenum or pylorus without significant obstruction were treated with a single gastric freeze for control of symptoms. From this group we have studied tissue from 15 stomachs surgically resected 3 to 537 days after gastric freezing.
Using the technique of Wangensteen and associates,2 gastric freezing was applied for a 60-minute period in all instances using a gastric hypothermia apparatus with a perfusion rate of 500 cc per minute. Inflow temperatures of −15 to −19 C and outflow temperatures of −10 to −14 C were maintained. The volume of the standard, latex rubber balloon was the maximal consistent with patient comfort and is recorded in Table 1. Body temperature was monitored with
BARNER HB, COLLINS CH, JONES TI, GARLICK TB. Morphology of Human Stomach After Therapeutic Freezing. Arch Surg. 1965;90(3):358-362. doi:10.1001/archsurg.1965.01320090036008