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April 1965

Postsystolic Myocardial AugmentationClinical Applications Utilizing the Pressure Pulse Generator

Author Affiliations

From the Professorial Surgical Unit, Denver General Hospital.

Arch Surg. 1965;90(4):544-553. doi:10.1001/archsurg.1965.01320100088014


DEMONSTRATION of the importance of accurate phasing in an arterioarterial system where the attempt is made to reduce the pressure-work load of the heart by withdrawing blood during the natural systole and reinjecting it during diastole was made in 1960 with the development of postsystolic myocardial augmentation.1,2 The theoretical, experimental, and clinical results obtained with the apparatus originally described have been so encouraging that now a completely automated system has been devised.

Theory of Operation  The pressure pulse generator is a device to generate a repetitive pulsatile pressure pulse wave. The timing of the pressure pulse wave is electronically controlled to maintain a precise phase relationship with the natural pulse pressure from the heart.During cardiac systole the heart ejects blood from the left ventricle into the aorta; in this action the heart exerts force to overcome the resistance to flow in the arterial tree. Under circumstances where

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