WITH THE development of low-priming volume oxygenators, assisted circulation has become available for emergency use. It has been suggested as treatment for a number of conditions including septicemic shock,1 cardiac arrest,2,3 pulmonary insufficiency,4 and congestive heart failure.5-12 Of these, emphasis has been placed on the use of circulatory support for the treatment of intractable heart failure after a myocardial infarction. The results, however, have been inconsistent and further evaluation of the use of assisted circulation in the treatment of heart failure is indicated.
In a previous publication,13 a technique was described for the production of experimental heart failure in animals by multiple coronary ligations. The resulting failure was found to be comparable to that occurring clinically following a myocardial infarction. The purpose of this study is to evaluate the effectiveness of various methods of assisted circulation in the treatment of experimental heart failure.
ELLIS PR, LEE C, WONG SH, DEL ROSARIO VC, HYLAND JW, PRATOR G. Assisted Circulation in Treatment of Experimental Heart Failure. Arch Surg. 1965;90(6):879-889. doi:10.1001/archsurg.1965.01320120081006