Transplanted tissue will grow only if there is a lack of that tissue in the host.
M ANY patients when deprived of all or a major portion of their stomachs are confronted with troublesome sequelae. Among the physiological changes suggested as responsible for some of these difficulties are such factors as mechanical, metabolic, functional, inflammatory, and hematologic.1,2 Attempts to overcome the mechanical factors have been widespread. In recent years numerous substitute pouches have been suggested.3-11 A long-term follow-up12 has indicated that the creation of a substitute pouch may possess some benefits but will by no means completely alleviate all postgastrectomy problems. Especially is this true in regard to loss of weight.
Previous experiments carried out in our laboratory have shown that the stomach may be relocated in the abdominal cavity as a pouch, yet continue to exert some salutary effects. It was concluded from these
GERWIG WH, ZIMMERMAN B, MENDOZA C, LEE RN, JONES CA, HOOTON TE. Activities of Transplanted Gastric Mucosa in the Totally Gastrectomized AnimalAn Experimental Study. Arch Surg. 1965;91(1):161-164. doi:10.1001/archsurg.1965.01320130163018