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Article
September 1965

Extracorporeal Circulation in Puppies

Author Affiliations

DENVER
From the Department of Surgery and the Halsted Laboratory for Experimental Surgery, University of Colorado Medical Center.

Arch Surg. 1965;91(3):513-515. doi:10.1001/archsurg.1965.01320150143028
Abstract

DESPITE increasing success in intracardiac surgery in the young infant, mortality rates are still high. Among the difficulties inherent in such surgery, extracorporeal circulation in young, small individuals plays a prominent role. For this reason, experience with cardiopulmonary bypass in small animals is essential for successful intracardiac surgery in infants.

Several authors1,7 have reported experiences with extracorporeal circulation in the puppy, and mortality rates have been high. The use of the dog for such experiments has been criticized, and an impression has been created that high mortality rates are to be expected.3

This paper reports initial experiences in this laboratory with extracorporeal circulation in young puppies and suggests that such procedures can be undertaken with reasonable expectation of success.

Material and Methods  Mongrel puppies weighing 2.14 to 5.58 kg (4.7 to 12.3 lb) were anesthetized with intravenous pentobarbital (Nembutal), and positive pressure respiration was maintained with warmed, humidified

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