October 1965

Electrophoresis of Chyle in Bronchogenic Carcinoma

Author Affiliations

From the Lymph Research Laboratory, Akron City Hospital.

Arch Surg. 1965;91(4):671-677. doi:10.1001/archsurg.1965.01320160125028

MANY REPORTS1-6 document the association of abnormal serum protein and lipoprotein electrophoretic patterns with various inflammatory and neoplastic diseases. The present report is concerned with similar determinations as well as with glycoprotein electrophoretic patterns in normal subjects and in patients afflicted either with inflammatory pulmonary disease or bronchogenic carcinoma. These determinations were carried out on the patient's serum, chyle, or lymph, or all.

Methods  In the 80 patients studied, bilateral scalene-lymphnode excisions and bilateral thoracic-duct cannulations7 were scheduled. Three hours prior to operation most patients were fed 4 to 6 oz of half milk and half cream (11.8% butterfat). After the induction of general anesthesia, a bronchoscopy and, infrequently, an esophagoscopy, or both, were followed by the bilateral scalene-lymph-node removal and thoracic-duct cannulation. Immediately after operation, samples of left and, when available, right thoracic-duct chyle or lymph were collected from the cannulae at the same time that venous-blood

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