THE ACID-BASE situation under hypothermic conditions is poorly understood because exact values for partial pressure of carbon dioxide (Pco2) and hydrogen ion content (pH) of whole blood under those conditions are difficult to determine. The values of Pco2 and pH in whole blood are important because the newer, electrometric analytical equipment can make these determinations accurately and rapidly on a sample of whole blood. In practice, the use of whole blood is time saving; it is always available and it does not require centrifugation.
By nature of the fluid, temperature coefficients for Pco2 and pH in whole blood cannot be derived theoretically; too many highly variable parameters would have to be dealt with.1 Therefore, empirically derived temperature coefficients for converting a Pco2 and pH determination at 37 C to a Pco2 and pH determination at a sample's original temperature are necessary.
Another reason temperature
GREENBURG AG, MOULDER PV. Temperature Coefficients for Pco2 and pH in Whole BloodFinding Pco2 and pH at Low Temperatures. Arch Surg. 1965;91(6):867-871. doi:10.1001/archsurg.1965.01320180001001