March 1966

Motor Responses of the Canine Stomach to Insulin and Feeding

Author Affiliations

From the Department of Surgery, Stanford University School of Medicine, Palo Alto.

Arch Surg. 1966;92(3):379-385. doi:10.1001/archsurg.1966.01320210059011

ACCURATE evaluation of the motor activity of the stomach requires a reliable technique which will sense peristaltic events without distortion or artifact. Normal peristalsis is customarily considered to be a series of progressive contractions which pass down the body and antrum of the stomach to the pylorus.1 Recording the dynamic and directional characteristics of gastric motility thus requires the use of multiple sensors of muscular activity whose anatomic locations remain relatively fixed in relationship to each other.

The muscular contractions of the stomach (and gut) generate the differential pressures in the gastrointestinal tract which are the forces responsible for the propulsion of its (fluid) contents. Most investigators have measured intraluminal pressures at one or more points in the stomach as a means of studying peristalsis.1-3 It is possible to relate observed intralumen pressure to wall tension in a hollow viscus by application of Poiseuille's law which states that

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