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April 1966

Intracranial SurgeryProfound Hypothermia and Cardiac Arrest

Author Affiliations

From Michael Reese Hospital and Medical Center, Chicago Medical School.

Arch Surg. 1966;92(4):573-575. doi:10.1001/archsurg.1966.01320220129021

ONE OF THE frequent problems in intracranial surgery is gaining control of the cerebral blood flow. It is difficult by conventional neurosurgical methods (ie, suction, cautery, etc) to obtain the hemostasis necessary to approach certain intracranial aneurysms and other vascular anomalies or tumors. When such a situation presents itself, special techniques are required to allow surgical correction of the lesion.

By combining profound hypothermia and cardiac arrest, the cerebral blood flow can be completely interrupted for extended periods of time.4 This prolonged duration of interruption of cerebral blood flow permits intracranial surgery under bloodless conditions. It has been shown by Gordon7 and others that when the temperature of the brain is reduced to between 12 and 15 C, the cerebral blood flow can safely be interrupted for periods up to one hour. On the basis of this work and the work of others, we have used profound hypothermia

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