June 1966

Current Concepts in the Management of Congenital Biliary Atresia

Author Affiliations

From the Department of Surgery, University of California at Los Angeles School of Medicine. Dr. Fonkalsrud is John and Mary R. Markle Scholar in Academic Medicine.

Arch Surg. 1966;92(6):813-817. doi:10.1001/archsurg.1966.01320240001001

CONGENITAL biliary atresia is one of the most serious malformations encountered by the physician who cares for infants and young children. Most infants with this anomaly die within the first two years of life since permanently effective drainage may not be established surgically between the biliary ductal system and the gastrointestinal tract.

The present study was undertaken to review the current management of this serious malformation based upon the experience with 27 infants with biliary atresia treated at the University of California, Los Angeles, during the ten-year period from 1955 to 1965.

In a program of aggressive surgical treatment for infants with biliary atresia, we have performed some type of biliary enteric decompression on 18 of the 27 patients (66.6%), eight of whom are presently alive (29.6%). These statistics are higher than those reported in the literature which cites operability for definitive cure between 15% and 25%1-4 and achievement

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