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June 1966

Primary Signet Ring Cell Carcinoma of the Urinary Bladder

Author Affiliations

From the departments of pathology and surgery, Veterans Administration Hospital, Clarksburg, and West Virginia University, Morgantown.

Arch Surg. 1966;92(6):958-959. doi:10.1001/archsurg.1966.01320240146032

THE INFREQUENCY of mucogenic adenocarcinoma of the urinary tract is easily appreciated by a review of the literature.1-5 Glandular tumors form approximately 1% of all tumors of the urinary bladder1 including tumors of the urachus and mucogenic adenocarcinomas from bladder origin.2,3 Seldom are signet ring cells of a substantial number encountered among the mucin-producing tumors of this organ. Saphir described one such case out of 271 carcinomas of the bladder.5 Association of bladder mucinous and transitional cell carcinomas were reported in six cases by Mostofi et al.3

The purpose of this report is to present a case of signet ring cell carcinoma of bladder origin associated with transitional cell carcinoma.

Report of Case  A 38-year-old white man was admitted to the hospital with hematuria of three weeks' duration. Past history and physical examination were unrevealing. No signs or symptoms of prostatic disease were noted. Findings

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