March 1967

Higher Homologous Cyanoacrylate Tissue Adhesives in Injured Kidney

Author Affiliations

USA; USA; USAR; USA, Washington, DC
From the Division of Surgery, Walter Reed Army Institute of Research, Washington, DC. Drs. Pani and Leonard are with the US Army Medical Biomechanical Research Laboratory, Washington, DC.

Arch Surg. 1967;94(3):392-395. doi:10.1001/archsurg.1967.01330090086022

ONE OF the keys to successful repair of the injured kidney is control of extensive hemorrhage from the cortex. It is obvious that a kidney worth saving should have an adequate blood supply. Therefore, at the present time, nephrectomy is warranted when the kidney, especially the renal cortex and vascular supply, is irretrievably damaged.

Nephrectomy carries minimum morbidity provided that the function of the opposite kidney is assured before surgery is undertaken. In many instances, packing to control hemorrhage and suture of renal pelvic tears are necessary together with perinephritic drainage or nephrectomy. The renal tissue withstands trauma well and may survive to function even in very unlikely circumstances. Therefore, if the hemorrhage from the renal cortex could be easily controlled, nephrectomy would be avoided.

In this work, control of bleeding was studied by use of the homologous series of α-cyanoacrylate adhesive monomers.

Material and Method  Butyl, amyl, heptyl cyanoacrylates

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