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November 1967

Acquired Aorto-arteritisA Worldwide Vascular Entity

Author Affiliations

Manila; New York
From the Department of Surgery, Philippine General Hospital and Surgical Research Laboratory, (Dr. Domingo) and Department of Pathology (Dr. Maramba), University of the Philippines; Department of Surgery, Philippine General Hospital (Dr. Torres), Manila; and State University of New York Downstate Medical Center, Brooklyn, and L.G.H. Laboratory, Mercy Hospital, Rockville Centre, New York (Dr. Wesolowski).

Arch Surg. 1967;95(5):780-790. doi:10.1001/archsurg.1967.01330170088012

THE original report of Takayasu in 1908 described unusual changes in the central retinal vessels. Subsequent reports in Japan and Europe, as summarized by McKusick,1 led to the acceptance of Takayasu's syndrome as an entity to indicate primary occlusive arteritis of the arch of the aorta. Such an entity has also been termed pulseless disease,2 aortic arch arteritis,3 aortic arch syndrome,4 and young female arteritis of aortic arch syndrome.5

In recent years, parallel with greater insight and more aggressive diagnostic approaches to vascular problems, reports show that a similar form of arteritis exists which is not confined to the aortic arch and its branches. It is of interest to note that such cases which have heretofore been considered of distinctly Asian origin6-13 affect the preatherosclerotic age group. The pathology in these reports is purely occlusive in nature and involves primarily the abdominal aorta and

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