December 1967

Microcirculation in Hemorrhagic Shock With Relationship to Blood Pressure

Author Affiliations

USA; USA; Washington, DC
From the Division of Surgery (Drs. Matsumoto and Hardaway) and the Photomicrography Section, Medical Audio Visual Branch (Mr. McClain), Walter Reed Army Institute of Research, Washington, DC.

Arch Surg. 1967;95(6):911-917. doi:10.1001/archsurg.1967.01330180059011

BLOOD pressure is measured as one index of the adequacy of the circulation. Circulating blood delivers to tissue adequate oxygen and carries away metabolic products. Adequate function depends on the volume of blood flow and rate. But Schumer et al1 reported that there was no correlation between blood pressure and the microcirculatory change. In fact, blood pressure can be quite independent of flow, and blood flow is not readily measured and the limits of volume perfusion related to metabolic activity of various tissues have not been defined.2

The purpose of this study was to observe the relationship of the microcirculation of the intestinal system and systemic arterial blood pressure in dog before and during shock.

Material and Method  Twenty mongrel dogs of both sexes weighing 8.9 to 19.6 kg were used. The principles of laboratory animal care as promulgated by the National Society for Medical Research were observed.

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